Run Exe On Windows 10

As already stated it will not run .exe files in normal mode, but works perfectly fine in safe mode. I have used two programs, McAfee and Malwarebytes, but no viruses were found. I was suggested Kasperskys but I cannot install this in safe mode.
Also, anything that I do manage to successfully open in normal mode either freezes or stops responding for long periods of time.
Additional information if necessary:
Manufacturer: Toshiba
Model: Satellite C655D
System type: 64-bit operating system
196 GB free out of 284

Windows 10 Won't Let Me Run Exe Files

Windows 10 Won't Run Exe Files On Mac

Jul 04, 2018  Value shown in video: '%1 ”%. You might encounter a situation where you may not be able to open any.exe files or shortcut link files, i.e., EXE or LNK files. You might instead get a “Open.